KETOPROFEN S
Ketoprofen S‑enantiomer is considered the more pharmacologically active form in COX inhibition and analgesia. It is investigated for optimized efficacy and safety profiles. Side effects remain similar to conventional ketoprofen, including GI irritation, bleeding risk, photosensitivity, and possible renal or cardiovascular effects in susceptible patients.
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Product Description
Mechanism of Action
KETOPROFEN S (ID 26497) exhibits a structured and multi‑layered biochemical activity profile involving modulation of enzymatic cascades, receptor‑binding dynamics, intracellular signalling architecture, and metabolic‑flux regulation. Its molecular characteristics indicate potential interactions with catalytic pockets, allosteric surfaces, and regulatory protein domains. Through these interactions, the compound influences phosphorylation patterns, mitochondrial bioenergetics, oxidative‑stress networks, membrane potential stabilization, and transcriptional pathway responsiveness.
In cellular systems, mechanistic effects may include modulation of calcium flux, ROS equilibrium, structural‑protein turnover, and adaptive stress‑response activation. The compound may act as a pathway booster, suppressor, or modulator depending on dosing, cellular environment, and metabolic state.
Benefits and Advantages
This compound is widely used in biochemical, pharmacological and mechanistic research settings, including:
- Receptor‑ligand interaction studies and affinity‑mapping assays
- Enzyme kinetics and catalytic‑pathway modelling
- Mitochondrial‑function, ROS‑regulation and redox‑balance experiments
- Transcriptomic, proteomic and metabolomic profiling
- Cell‑stress signalling, apoptosis/autophagy pathway mapping and cytoskeletal‑dynamics studies
- Pharmacodynamic simulation and SAR (structure‑activity relationship) analysis
Side Effects and Risks
Risks may include unintended oxidative imbalance, mitochondrial overload, receptor cross‑talk effects, disruption of ion‑channel homeostasis, and dose‑dependent cytotoxicity. At elevated concentrations, the compound may trigger apoptosis, autophagy, or compensatory metabolic rewiring. Long‑term exposure can influence transcriptional stability, signalling thresholds, and cellular resilience.
Use only in controlled laboratory environments following strict biosafety and handling protocols. Not intended for human or veterinary use.
Datasheet
| Molecular Formula | C16H14O3 |
|---|---|
| Molecular Weight | 254.28 g/mol |
| CAS Number | 22161-81-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | ketoprofen; 22071-15-4; 2-(3-Benzoylphenyl)propanoic acid; 2-(3-Benzoylphenyl)propionic acid; Orudis |
| IUPAC/Chemical Name | (S)-2-(3-benzoylphenyl)propionic acid |
| InChl Key | DKYWVDODHFEZIM-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19) |
| References |
3D Conformer.
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