ISOXSUPRINE HYDROCHLORIDE
Isoxsuprine hydrochloride is a vasodilator and agonist that relaxes vascular and uterine smooth muscle, improving peripheral blood flow. It has been used in peripheral vascular disease and to reduce uterine tone. Benefits include enhanced tissue perfusion and decreased spasms. Side effects may include tachycardia, flushing, hypotension, headache, and nervousness. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
ISOXSUPRINE HYDROCHLORIDE exhibits complex multipathway biochemical interactions involving receptorlevel modulation, regulatory enzyme interference, intracellular signalling adjustment and transcriptomic pathway influence. Its physicochemical profile suggests affinity for catalytic and regulatory protein domains, enabling disruption or enhancement of phosphorylation cycles, redoxstate balance, and mitochondrial performance. In several experimental systems, the compound demonstrates capacity to alter calcium signalling, membrane potential, structuralprotein dynamics and cellular metabolic flux.
Benefits and Advantages
This compound supports highresolution biochemical modelling and is suitable for use in:
- Receptorligand binding studies and pathway validation
- Metabolicflux assays, mitochondrialstress evaluations and ROSregulation research
- Multiomics profiling (transcriptomics, metabolomics, proteomics)
- Stressresponse signalling, kinase/phosphatase cascade mapping and cytoskeletal dynamics analysis
- Earlyphase pharmacodynamic screening and SAR exploration
Side Effects and Risks
Potential risks include redox imbalance, mitochondrial overload, cytoskeletal disruption, altered membrane integrity, aberrant calcium flux, and dosedependent cytotoxicity. At elevated concentrations, the compound may induce apoptosis, autophagy, or transcriptional stress responses. Use only under strict laboratory conditions with appropriate biosafety protocols and controlled exposure.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C18H24ClNO3 |
|---|---|
| Molecular Weight | 337.8 g/mol |
| CAS Number | 579-56-6 |
| Storage Condition | Isoxsuprine hydrochloride tablets should be stored in tight containers at a temp <40 °C, preferably between 15-30 °C. |
| Solubility | Soluble in ethanol |
| Purity | Purity information is available upon request (COA). |
| Synonym | Isoxsuprine hydrochloride; 579-56-6; Isoxsuprine HCl; Duvadilan; Dilavase |
| IUPAC/Chemical Name | 4-[1-hydroxy-2-(1-phenoxypropan-2-ylamino)propyl]phenol;hydrochloride |
| InChl Key | QVPSGVSNYPRFAS-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H23NO3.ClH/c1-13(12-22-17-6-4-3-5-7-17)19-14(2)18(21)15-8-10-16(20)11-9-15;/h3-11,13-14,18-21H,12H2,1-2H3;1H |
| References |
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