IPRATROPIUM BROMIDE

Ipratropium bromide is an anticholinergic bronchodilator reducing bronchospasm in COPD and asthma. Side effects include dry mouth, cough, and throat irritation. Only GMP materials will be supplied, logistics all according to GDP.

SKU: b2d8af30802b Category: Tag:

Product Description


Mechanism of Action

IPRATROPIUM BROMIDE exhibits complex multipathway biochemical interactions involving receptorlevel modulation, regulatory enzyme interference, intracellular signalling adjustment and transcriptomic pathway influence. Its physicochemical profile suggests affinity for catalytic and regulatory protein domains, enabling disruption or enhancement of phosphorylation cycles, redoxstate balance, and mitochondrial performance. In several experimental systems, the compound demonstrates capacity to alter calcium signalling, membrane potential, structuralprotein dynamics and cellular metabolic flux.

Benefits and Advantages

This compound supports highresolution biochemical modelling and is suitable for use in:

  • Receptorligand binding studies and pathway validation
  • Metabolicflux assays, mitochondrialstress evaluations and ROSregulation research
  • Multiomics profiling (transcriptomics, metabolomics, proteomics)
  • Stressresponse signalling, kinase/phosphatase cascade mapping and cytoskeletal dynamics analysis
  • Earlyphase pharmacodynamic screening and SAR exploration

Side Effects and Risks

Potential risks include redox imbalance, mitochondrial overload, cytoskeletal disruption, altered membrane integrity, aberrant calcium flux, and dosedependent cytotoxicity. At elevated concentrations, the compound may induce apoptosis, autophagy, or transcriptional stress responses. Use only under strict laboratory conditions with appropriate biosafety protocols and controlled exposure.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C20H30BrNO3

Molecular Weight

412.4 g/mol

CAS Number

22254-24-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

(endo,Anti)-(1)-3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-isopropyl-8-methyl-8-azoniabicyclo(3.2.1)octane bromide; RefChem:1050959; ipratropium bromide; 22254-24-6; Atrovent

IUPAC/Chemical Name

[(1S,5R)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate bromide

InChl Key

LHLMOSXCXGLMMN-CLTUNHJMSA-M

InChl Code

InChI=1S/C20H30NO3.BrH/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15;/h4-8,14,16-19,22H,9-13H2,1-3H3;1H/q+1;/p-1/t16-,17+,18?,19?,21?;

References

https://pubchem.ncbi.nlm.nih.gov/compound/657308;

3D Conformer.

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