INFLIXIMAB

Infliximab is a monoclonal antibody blocking TNF to treat autoimmune diseases. Side effects include infections, infusion reactions, and fatigue. Only GMP materials will be supplied, logistics all according to GDP.

SKU: d0f025297cfa Category: Tag:

Product Description


Mechanism of Action

INFLIXIMAB exhibits a multi-dimensional biochemical activity profile that affects cellular regulation at enzyme, receptor, and transcriptional levels. Its molecular interactions can alter phosphorylation cycles, modulate ionic homeostasis, influence mitochondrial respiration, and adjust redox-signaling pathways. Structural properties suggest specific affinity for regulatory proteins, enabling modulation of metabolic flux and cellular response thresholds.

Benefits and Advantages

This compound is suited for high-resolution mechanistic research, multiomics integration studies, receptor-binding experiments, enzyme-pathway mapping, and advanced pharmacodynamic modelling. It supports ROS-regulation assays, signalling-cascade analysis, cytoskeletaldynamics research, and metabolic adaptation models. Due to predictable biochemical behaviour, it is often used as a comparative reference in pathwayperturbation studies.

  • Useful in mechanistic pharmacology and biochemical modelling
  • Applicable in oxidative-stress, mitochondrial-function and signalling studies
  • Reliable for transcriptional and proteomic profiling
  • Supports SAR (structureactivity relationship) investigations

Side Effects and Risks

Potential risks include mitochondrial overload, ROS imbalance, inadvertent receptor crosstalk, disruption of ion-channel dynamics, and dose-dependent cytotoxicity. High exposure may trigger apoptosis, autophagy, or cellular stress-response activation. Controlled handling conditions and biosafety protocols are required for laboratory use.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

Protein

Molecular Weight

149000.0 g/mol

CAS Number

170277-31-3

Storage Condition

Store at 2-8°C

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

IUPAC/Chemical Name

Monoclonal antibody

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

3D Conformer.

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