HOMOVANILLIC ACID

Homovanillic acid is a dopamine metabolite used as a biomarker in neurological research. Side effects are minimal and mainly exposure-related. Only GMP materials will be supplied, logistics all according to GDP.

SKU: a1f1efe5afcc Category: Tag:

Product Description


Mechanism of Action

HOMOVANILLIC ACID exhibits a complex biochemical signature characterized by multipathway modulation involving receptor interaction, enzymatic pathway alteration, mitochondrial signalling influence and transcriptionlevel regulation. Its molecular structure suggests affinity for catalytic domains and regulatory protein surfaces, enabling modulation of phosphorylation cycles, redox equilibrium, metabolic flux and intracellular secondmessenger dynamics. Through these combined mechanisms, the compound can shift cellular homeostasis, alter stressresponse thresholds, and influence adaptive pathway activation.

Benefits and Advantages

This compound is used extensively in advanced biochemical modelling, mechanistic pathway validation, receptorligand binding experiments, ROSmodulation studies, mitochondrialfunction assays, kinase/phosphatase cascade mapping and earlystage pharmacodynamic screening. Its stable and reproducible activity allows highfidelity comparative assays, multiomics profiling (proteomic, metabolomic and transcriptomic), and SAR exploration.

  • Supports highresolution mechanistic research
  • Useful for controlled pathway perturbation models
  • Applicable in metabolic and endocrine modelling
  • Valuable for cytotoxicity, redox and stressresponse assays

Side Effects and Risks

Potential risks include mitochondrial overload, ROS imbalance, offtarget receptor or enzyme interactions, modulation of cytoskeletal integrity, calciumflux disruption and dosedependent apoptotic or autophagic signalling. High exposure or chronic application may alter metabolic gene expression or induce compensatory stress pathways.

Use only in controlled laboratory environments following appropriate biosafety and chemicalhandling protocols.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C9H10O4

Molecular Weight

182.17 g/mol

CAS Number

306-08-1

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

17 mg/mL

Purity

Purity information is available upon request (COA).

Synonym

Homovanillic acid; 306-08-1; 4-Hydroxy-3-methoxyphenylacetic acid; 2-(4-hydroxy-3-methoxyphenyl)acetic acid; Benzeneacetic acid, 4-hydroxy-3-methoxy-

IUPAC/Chemical Name

2-(4-hydroxy-3-methoxyphenyl)acetic acid

InChl Key

QRMZSPFSDQBLIX-UHFFFAOYSA-N

InChl Code

InChI=1S/C9H10O4/c1-13-8-4-6(5-9(11)12)2-3-7(8)10/h2-4,10H,5H2,1H3,(H,11,12)

References

https://pubchem.ncbi.nlm.nih.gov/compound/1738;

3D Conformer.

(Click, turn or enlarge)

Download our GMP API Product List.

MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.

Download