HEXACHLORETHANE

Hexachloroethane is an antihelminthic and industrial compound historically used for parasitic infections. Side effects include liver toxicity and CNS symptoms.

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Product Description


Mechanism of Action

HEXACHLORETHANE (ID 26333) exhibits a complex biochemical signature characterized by multi‑pathway modulation involving receptor interaction, enzymatic pathway alteration, mitochondrial signalling influence and transcription‑level regulation. Its molecular structure suggests affinity for catalytic domains and regulatory protein surfaces, enabling modulation of phosphorylation cycles, redox equilibrium, metabolic flux and intracellular second‑messenger dynamics. Through these combined mechanisms, the compound can shift cellular homeostasis, alter stress‑response thresholds, and influence adaptive pathway activation.

Benefits and Advantages

This compound is used extensively in advanced biochemical modelling, mechanistic pathway validation, receptor‑ligand binding experiments, ROS‑modulation studies, mitochondrial‑function assays, kinase/phosphatase cascade mapping and early‑stage pharmacodynamic screening. Its stable and reproducible activity allows high‑fidelity comparative assays, multi‑omics profiling (proteomic, metabolomic and transcriptomic), and SAR exploration.

  • Supports high‑resolution mechanistic research
  • Useful for controlled pathway perturbation models
  • Applicable in metabolic and endocrine modelling
  • Valuable for cytotoxicity, redox and stress‑response assays

Side Effects and Risks

Potential risks include mitochondrial overload, ROS imbalance, off‑target receptor or enzyme interactions, modulation of cytoskeletal integrity, calcium‑flux disruption and dose‑dependent apoptotic or autophagic signalling. High exposure or chronic application may alter metabolic gene expression or induce compensatory stress pathways.

Use only in controlled laboratory environments following appropriate biosafety and chemical‑handling protocols.

Datasheet


Molecular Formula

C2Cl6

Molecular Weight

236.7 g/mol

CAS Number

67-72-1

Storage Condition

…Hexachloroethane must be stored to avoid contact with hot iron, zinc, aluminum, and alkalis, since violent reactions occur. Store in tightly closed containers in a cool, well-ventilated area away from heat.

Solubility

less than 1 mg/mL at 70 °F (NTP, 1992)

Purity

Purity information is available upon request (COA).

Synonym

HEXACHLOROETHANE; 67-72-1; Perchloroethane; Ethane, hexachloro-; Avlothane

IUPAC/Chemical Name

1,1,1,2,2,2-hexachloroethane

InChl Key

VHHHONWQHHHLTI-UHFFFAOYSA-N

InChl Code

InChI=1S/C2Cl6/c3-1(4,5)2(6,7)8

References

https://pubchem.ncbi.nlm.nih.gov/compound/6214;

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