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Product Description
Mechanism of Action
Glimepiride stimulates insulin release through KATP-channel closure and enhances peripheral glucose uptake via insulin-sensitizing secondary pathways.
Benefits and Advantages
Used in glucose-regulation studies, sulfonylurea SAR work, metabolic modelling and beta-cell function assays.
Side Effects and Risks
Hypoglycemia, dizziness and hepatic enzyme elevation.
Datasheet
| Molecular Formula | C24H34N4O5S |
|---|---|
| Molecular Weight | 490.6 g/mol |
| CAS Number | 93479-97-1 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | 3.84e-02 g/L |
| Purity | Purity information is available upon request (COA). |
| Synonym | 1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-; 1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-2-4-(trans-4-methylcyclohexyl)aminocarbonylaminosulfonylphenylethyl-2-oxo-; 1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-(2-(4-(((((trans-4-methylcyclohexyl)amino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-oxo-; RefChem:439179; glimepiride |
| IUPAC/Chemical Name | 4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide |
| InChl Key | WIGIZIANZCJQQY-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30) |
| References |
3D Conformer.
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