GESTRINONE
Gestrinone is a steroidal agent with anti‑estrogenic and anti‑progestogenic effects used in endometriosis. Side effects include acne, weight gain, and voice changes.
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Product Description
Mechanism of Action
Gestrinone is a synthetic steroid with mixed progestogenic, antiestrogenic and androgenic activity, modulating multiple hormone receptors and suppressing endometrial proliferation.
Benefits and Advantages
Used in endocrine-pathway modelling, receptor-binding assays, reproductive research and estrogen-antagonism studies.
Side Effects and Risks
Acne, weight changes, masculinization effects and hormonal fluctuations.
Datasheet
| Molecular Formula | C21H24O2 |
|---|---|
| Molecular Weight | 308.4 g/mol |
| CAS Number | 16320-04-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Gestrinone; 16320-04-0; Dimetriose; Ethylnorgestrienone; Gestrinona |
| IUPAC/Chemical Name | (8S,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |
| InChl Key | BJJXHLWLUDYTGC-ANULTFPQSA-N |
| InChl Code | InChI=1S/C21H24O2/c1-3-20-11-9-17-16-8-6-15(22)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,9,11,13,18-19,23H,3,5-8,10,12H2,1H3/t18-,19+,20+,21+/m1/s1 |
| References |
3D Conformer.
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