GANCICLOVIR
Ganciclovir is an antiviral inhibiting viral DNA polymerase, used for CMV infections. Side effects include bone marrow suppression, nephrotoxicity, and GI upset. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Ganciclovir is a nucleoside analogue antiviral that undergoes phosphorylation by viral kinases and inhibits viral DNA polymerase, causing chain termination and halting replication of CMV and other herpesviruses.
Benefits and Advantages
Used in DNA-polymerase inhibition studies, CMV replication research, antiviral resistance modelling and nucleoside analogue SAR assays.
Side Effects and Risks
Myelosuppression, nephrotoxicity and reproductive risks. Handle with antiviral-cytotoxic precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C9H13N5O4 |
|---|---|
| Molecular Weight | 255.23 g/mol |
| CAS Number | 82410-32-0 |
| Storage Condition | Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 – 8 °C. Keep in a dry place. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | ganciclovir; 82410-32-0; Gancyclovir; Vitrasert; Zirgan |
| IUPAC/Chemical Name | 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-1H-purin-6-one |
| InChl Key | IRSCQMHQWWYFCW-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17) |
| References |
3D Conformer.
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