GABEXATE MESYLATE
Gabexate mesylate provides similar protease inhibition with improved formulation. Side effects include GI discomfort, rash, and infusion reactions.
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Product Description
Mechanism of Action
Gabexate mesylate is the mesylate salt of gabexate, improving aqueous solubility for parenteral use while maintaining potent serine‑protease inhibition of trypsin, plasmin, kallikrein and thrombin. It modulates coagulation and inflammatory cascades in plasma.
Benefits and Advantages
Used in IV formulation research, DIC and pancreatitis models, kallikrein–kinin system studies and protease‑network analysis.
Side Effects and Risks
Possible hypotension, bleeding tendency, local venous irritation and allergic reactions. Handle as a parenteral protease inhibitor with appropriate hemostatic monitoring.
Datasheet
| Molecular Formula | C15H23N3O5·CH4O3S |
|---|---|
| Molecular Weight | 417.5 g/mol |
| CAS Number | 56974-61-9 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Gabexate mesylate; 56974-61-9; Gabexate mesilate; Gabexate mesilate [JAN]; Arodate (TN) |
| IUPAC/Chemical Name | ethyl 4-[6-(diaminomethylideneamino)hexanoyloxy]benzoate;methanesulfonic acid |
| InChl Key | DNTNDFLIKUKKOC-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C16H23N3O4.CH4O3S/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18;1-5(2,3)4/h7-10H,2-6,11H2,1H3,(H4,17,18,19);1H3,(H,2,3,4) |
| References |
3D Conformer.
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