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Product Description
Mechanism of Action
Furosemide sodium is a water‑soluble salt form of furosemide, retaining full inhibition of the Na⁺‑K⁺‑2Cl⁻ cotransporter in the loop of Henle. The sodium salt improves solubility for injectable and concentrated formulations while maintaining potent loop‑diuretic activity.
Benefits and Advantages
Used in parenteral formulation research, high‑solubility diuretic studies, rapid‑onset diuresis modelling and NKCC2‑target assays.
Side Effects and Risks
Similar to furosemide: electrolyte depletion, dehydration, ototoxicity and hypotension. Handle with loop‑diuretic precautions and careful dose‑response evaluation.
Datasheet
| Molecular Formula | C12H10ClN2O5SNa |
|---|---|
| Molecular Weight | 352.73 g/mol |
| CAS Number | 41733-55-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Furosemide sodium; Sodium furosemide; 41733-55-5; Frosemide sodium; UNII-101EM454S7 |
| IUPAC/Chemical Name | sodium 4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoate |
| InChl Key | DLFCAVBMDSKMEY-UHFFFAOYSA-M |
| InChl Code | InChI=1S/C12H11ClN2O5S.Na/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19;/h1-5,15H,6H2,(H,16,17)(H2,14,18,19);/q;+1/p-1 |
| References |
3D Conformer.
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