About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Ftorafur (tegafur) is a prodrug of 5fluorouracil that undergoes CYPmediated activation, gradually releasing 5FU to inhibit thymidylate synthase and RNA/DNA synthesis.
Benefits and Advantages
Used in prodrugactivation studies, oncologic cytotoxicity assays, TSinhibition modelling and combinationtherapy research.
Side Effects and Risks
Myelosuppression, GI toxicity, neurotoxicity and dermatologic reactions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C8H9FN2O3 |
|---|---|
| Molecular Weight | 200.17 g/mol |
| CAS Number | 17902-23-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Partly miscible |
| Purity | Purity information is available upon request (COA). |
| Synonym | tegafur; 17902-23-7; Ftorafur; Futraful; Sinoflurol |
| IUPAC/Chemical Name | 5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione |
| InChl Key | WFWLQNSHRPWKFK-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C8H9FN2O3/c9-5-4-11(6-2-1-3-14-6)8(13)10-7(5)12/h4,6H,1-3H2,(H,10,12,13) |
| References |
3D Conformer.
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