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Product Description
Mechanism of Action
Framycetin sulfate (neomycin B) is an aminoglycoside antibiotic that binds the 30S ribosomal subunit, inhibiting protein synthesis and causing translational errors.
Benefits and Advantages
Used in ribosomal fidelity studies, antimicrobial‑resistance modelling and aminoglycoside SAR research.
Side Effects and Risks
Nephrotoxicity, ototoxicity and contact sensitization.
Datasheet
| Molecular Formula | C23H48N6O17S |
|---|---|
| Molecular Weight | 712.7 g/mol |
| CAS Number | 1405-10-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | NEOMYCIN SULFATE; Neomycin B sulfate; 1405-10-3; Neomycin sulphate; Bykomycin |
| IUPAC/Chemical Name | (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid |
| InChl Key | OIXVKQDWLFHVGR-WQDIDPJDSA-N |
| InChl Code | InChI=1S/C23H46N6O13.H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1 |
| References |
3D Conformer.
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