FOSCARNET SODIUM

Foscarnet sodium is a pyrophosphate analogue that inhibits viral DNA polymerase, used for CMV and acyclovir‑resistant HSV infections. Side effects include nephrotoxicity, electrolyte disturbances, and genital irritation.

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Product Description


Mechanism of Action

Foscarnet sodium inhibits viral DNA polymerase, reverse transcriptase and RNA polymerase by acting as a pyrophosphate analogue that blocks nucleotide‑binding sites.

Benefits and Advantages

Used in herpesvirus and HIV polymerase inhibition studies, antiviral SAR modelling and nucleotide‑pathway research.

Side Effects and Risks

Nephrotoxicity, electrolyte imbalance and CNS toxicity.

Datasheet


Molecular Formula

CNa3O5P

Molecular Weight

191.95 g/mol

CAS Number

63585-09-1

Storage Condition

Store at 20 to 25 °C (68 to 77 °F). Protect from excessive heat (above 40 °C) and from freezing.

Solubility

Complete

Purity

Purity information is available upon request (COA).

Synonym

FOSCARNET SODIUM; 63585-09-1; Foscavir; Foscarnet sodico; EHB 776

IUPAC/Chemical Name

trisodium;phosphonatoformate

InChl Key

DFHAXXVZCFXGOQ-UHFFFAOYSA-K

InChl Code

InChI=1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3

References

https://pubchem.ncbi.nlm.nih.gov/compound/44561;

3D Conformer.

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