FOSCARNET SODIUM
Foscarnet sodium is a pyrophosphate analogue that inhibits viral DNA polymerase, used for CMV and acyclovir‑resistant HSV infections. Side effects include nephrotoxicity, electrolyte disturbances, and genital irritation.
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Product Description
Mechanism of Action
Foscarnet sodium inhibits viral DNA polymerase, reverse transcriptase and RNA polymerase by acting as a pyrophosphate analogue that blocks nucleotide‑binding sites.
Benefits and Advantages
Used in herpesvirus and HIV polymerase inhibition studies, antiviral SAR modelling and nucleotide‑pathway research.
Side Effects and Risks
Nephrotoxicity, electrolyte imbalance and CNS toxicity.
Datasheet
| Molecular Formula | CNa3O5P |
|---|---|
| Molecular Weight | 191.95 g/mol |
| CAS Number | 63585-09-1 |
| Storage Condition | Store at 20 to 25 °C (68 to 77 °F). Protect from excessive heat (above 40 °C) and from freezing. |
| Solubility | Complete |
| Purity | Purity information is available upon request (COA). |
| Synonym | FOSCARNET SODIUM; 63585-09-1; Foscavir; Foscarnet sodico; EHB 776 |
| IUPAC/Chemical Name | trisodium;phosphonatoformate |
| InChl Key | DFHAXXVZCFXGOQ-UHFFFAOYSA-K |
| InChl Code | InChI=1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3 |
| References |
3D Conformer.
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