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Product Description
Mechanism of Action
Formestane is a steroidal aromatase inhibitor that irreversibly inactivates CYP19A1, reducing estrogen biosynthesis and suppressing estrogen‑dependent cell growth.
Benefits and Advantages
Used in endocrine‑axis studies, aromatase inhibition assays and hormone‑responsive tumour modelling.
Side Effects and Risks
Hot flashes, bone density loss, fatigue and androgenic effects.
Datasheet
| Molecular Formula | C19H26O3 |
|---|---|
| Molecular Weight | 302.4 g/mol |
| CAS Number | 566-48-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Insoluble |
| Purity | Purity information is available upon request (COA). |
| Synonym | formestane; 566-48-3; 4-Hydroxyandrost-4-ene-3,17-dione; 4-Hydroxyandrostenedione; Lentaron |
| IUPAC/Chemical Name | (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione |
| InChl Key | OSVMTWJCGUFAOD-KZQROQTASA-N |
| InChl Code | InChI=1S/C19H26O3/c1-18-10-8-15(20)17(22)14(18)4-3-11-12-5-6-16(21)19(12,2)9-7-13(11)18/h11-13,22H,3-10H2,1-2H3/t11-,12-,13-,18+,19-/m0/s1 |
| References |
3D Conformer.
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