FLUTAMIDE

Flutamide is a nonsteroidal antiandrogen blocking androgen receptors in prostate cancer. Side effects include liver toxicity, gynecomastia, and hot flashes.

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Product Description


Mechanism of Action

Flutamide is a non‑steroidal androgen‑receptor antagonist that blocks DHT/testosterone activity, inhibiting androgen‑dependent growth.

Benefits and Advantages

Used in prostate‑cancer modelling, AR‑pathway assays and endocrine disruption research.

Side Effects and Risks

Hepatotoxicity, gynecomastia, GI upset and endocrine changes.

Datasheet


Molecular Formula

C11H11F3N2O3

Molecular Weight

276.21 g/mol

CAS Number

13311-84-7

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

flutamide; 13311-84-7; Eulexin; Niftolide; 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

IUPAC/Chemical Name

2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

InChl Key

MKXKFYHWDHIYRV-UHFFFAOYSA-N

InChl Code

InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17)

References

https://pubchem.ncbi.nlm.nih.gov/compound/3397;

3D Conformer.

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