FLUTAMIDE
Flutamide is a nonsteroidal antiandrogen blocking androgen receptors in prostate cancer. Side effects include liver toxicity, gynecomastia, and hot flashes.
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Product Description
Mechanism of Action
Flutamide is a non‑steroidal androgen‑receptor antagonist that blocks DHT/testosterone activity, inhibiting androgen‑dependent growth.
Benefits and Advantages
Used in prostate‑cancer modelling, AR‑pathway assays and endocrine disruption research.
Side Effects and Risks
Hepatotoxicity, gynecomastia, GI upset and endocrine changes.
Datasheet
| Molecular Formula | C11H11F3N2O3 |
|---|---|
| Molecular Weight | 276.21 g/mol |
| CAS Number | 13311-84-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | flutamide; 13311-84-7; Eulexin; Niftolide; 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide |
| IUPAC/Chemical Name | 2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide |
| InChl Key | MKXKFYHWDHIYRV-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C11H11F3N2O3/c1-6(2)10(17)15-7-3-4-9(16(18)19)8(5-7)11(12,13)14/h3-6H,1-2H3,(H,15,17) |
| References |
3D Conformer.
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