FLUPREDNIDENE
Fluprednidene is a corticosteroid reducing inflammation in dermatologic disorders. Side effects include irritation, skin thinning, and dryness. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Fluprednidene is a glucocorticoid that suppresses inflammatory mediators by inhibiting phospholipase A2 and NF-κB signalling.
Benefits and Advantages
Used in topical antiinflammatory studies, corticosteroid modelling and immuneresponse suppression research.
Side Effects and Risks
Skin atrophy, adrenal suppression and pigmentation shifts.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C22H27FO5 |
|---|---|
| Molecular Weight | 390.4 g/mol |
| CAS Number | 2193-87-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Fluprednidene; 2193-87-5; Fluprednideno; Fluprednidenum; Fluprednidenum [INN-Latin] |
| IUPAC/Chemical Name | (8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylidene-7,8,11,12,14,15-hexahydro-6H-cyclopenta[a]phenanthren-3-one |
| InChl Key | YVHXHNGGPURVOS-SBTDHBFYSA-N |
| InChl Code | InChI=1S/C22H27FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,15-17,24,26,28H,1,4-5,8,10-11H2,2-3H3/t15-,16-,17-,19-,20-,21-,22-/m0/s1 |
| References |
3D Conformer.
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