FLUOROURACIL
Fluorouracil is a research-grade compound used in advanced pharmaceutical and biochemical studies. Chemical & Pharmacological Characteristics Physicochemical properties such as solubility, stability, and ionization state govern behavior in experimental systems. Mechanism of Action No single receptor-driven mechanism applies; observed effects are concentration- and context-dependent. Interpretation requires matched controls to separate direct chemical effects from secondary stress responses. It is primarily applied to investigate compound-specific mechanisms, physicochemical behavior, and analytical or formulation-relevant characteristics under controlled laboratory conditions.
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Product Description
Chemical & Pharmacological Characteristics
Physicochemical properties such as solubility, stability, and ionization state govern behavior in experimental systems.
Mechanism of Action
No single receptor-driven mechanism applies; observed effects are concentration- and context-dependent.
Interpretation requires matched controls to separate direct chemical effects from secondary stress responses.
Advanced Research Applications
- Analytical reference and quality control testing
- Formulation development and stability investigations
- Compatibility screening with excipients and packaging
- Comparative toxicology assessments where applicable
- Documentation support for R&D workflows
Toxicodynamics & Cellular Hazard Spectrum
- Nonspecific cytotoxicity at high exposure
- Solubility or aggregation-driven assay artifacts
- Matrix-dependent assay interference
- Handling irritation potential
- Dispose according to laboratory waste regulations
For expert laboratory research only – not intended for biological or therapeutic exposure.
Datasheet
| Molecular Formula | C4H3FN2O2 |
|---|---|
| Molecular Weight | 130.08 g/mol |
| CAS Number | 51-21-8 |
| Storage Condition | Store at 25 °C (77 °F); excursions permitted to 15 °C – 30 °C (59 °F -86 °F). /Efudex Solutions/ |
| Solubility | less than 1 mg/mL at 66 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | 5-Fluorouracil; fluorouracil; 51-21-8; Efudex; Fluracil |
| IUPAC/Chemical Name | 5-fluoro-1H-pyrimidine-2,4-dione |
| InChl Key | GHASVSINZRGABV-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9) |
| References | https://pubchem.ncbi.nlm.nih.gov/compound/3385; small-molecule |
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