FLUOROCYTOSINE

Fluorocytosine is an antifungal precursor to 5‑FU inhibiting nucleic acid synthesis. Side effects include bone marrow suppression and hepatotoxicity.

SKU: dce311b72c90 Category: Tag:

Product Description


Mechanism of Action

Fluorocytosine (5‑FC) is converted by fungal cytosine deaminase to 5‑FU, disrupting RNA and DNA synthesis in susceptible fungi.

Benefits and Advantages

Used in antifungal synergy research, nucleic‑acid pathway analysis and fungal metabolism modelling.

Side Effects and Risks

Bone‑marrow suppression, GI toxicity and hepatotoxicity.

Datasheet


Molecular Formula

C4H4FN3O

Molecular Weight

129.09 g/mol

CAS Number

2022-85-7

Storage Condition

Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep in a dry place.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

5-Fluorocytosine; flucytosine; 2022-85-7; Fluorocytosine; Ancobon

IUPAC/Chemical Name

6-amino-5-fluoro-1H-pyrimidin-2-one

InChl Key

XRECTZIEBJDKEO-UHFFFAOYSA-N

InChl Code

InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9)

References

https://pubchem.ncbi.nlm.nih.gov/compound/3366;

3D Conformer.

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