FLUORAURACIL

Fluorouracil is a pyrimidine analogue inhibiting thymidylate synthase, used in cancers. Side effects include myelosuppression, mucositis, and photosensitivity.

SKU: 6801f8b9a8e8 Category: Tag:

Product Description


Mechanism of Action

Fluorouracil (5‑FU) inhibits thymidylate synthase and incorporates into RNA and DNA, disrupting nucleic acid synthesis in rapidly dividing cells.

Benefits and Advantages

Used in cancer cytotoxicity research, TS‑inhibition assays and RNA/DNA synthesis modelling.

Side Effects and Risks

Myelosuppression, mucositis, cardiotoxicity and dermatologic reactions.

Datasheet


Molecular Formula

C4H3FN2O2

Molecular Weight

130.08 g/mol

CAS Number

51-21-8

Storage Condition

Store in a cool, dry place; protect from light

Solubility

Soluble in water

Purity

Purity information is available upon request (COA).

Synonym

5-Fluorouracil; fluorouracil; 51-21-8; Efudex; Fluracil

IUPAC/Chemical Name

5-fluoro-1H-pyrimidine-2,4-dione

InChl Key

Unavailable

InChl Code

Unavailable

References

PubChem; ChemBL; FDA;

3D Conformer.

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