FLUOCINONIDE

Fluocinonide is a high‑potency topical corticosteroid reducing inflammation in dermatoses. Side effects include burning, thinning skin, and telangiectasia.

SKU: 97367c45a80e Category: Tag:

Product Description


Mechanism of Action

Fluocinonide is a potent corticosteroid that suppresses inflammatory cytokines, reduces vasodilation and decreases immune‑cell activity.

Benefits and Advantages

Used in dermatologic models, steroid‑response assays and cytokine‑suppression research.

Side Effects and Risks

Local irritation, systemic absorption risk and atrophy.

Datasheet


Molecular Formula

C26H32F2O7

Molecular Weight

494.5 g/mol

CAS Number

356-12-7

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

fluocinonide; 356-12-7; Lidex; Fluocinolide; Vanos

IUPAC/Chemical Name

[2-[(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] acetate

InChl Key

WJOHZNCJWYWUJD-IUGZLZTKSA-N

InChl Code

InChI=1S/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15-,16-,18-,19-,21+,23-,24-,25-,26+/m0/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/9642;

3D Conformer.

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