FLUOCINOLONE ACETONIDE

Fluocinolone acetonide is a corticosteroid reducing skin inflammation and itching. Side effects include dryness, irritation, and long‑term atrophy.

SKU: 31d500758a69 Category: Tag:

Product Description


Mechanism of Action

Fluocinolone acetonide is a high‑potency glucocorticoid that modulates inflammatory gene expression and inhibits leukocyte migration.

Benefits and Advantages

Used in dermatologic inflammation studies, GR‑signalling assays and topical formulation development.

Side Effects and Risks

Skin thinning, adrenal suppression and pigmentation changes.

Datasheet


Molecular Formula

C24H30O6

Molecular Weight

452.5 g/mol

CAS Number

67-73-2

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Insoluble

Purity

Purity information is available upon request (COA).

Synonym

FLUOCINOLONE ACETONIDE; 67-73-2; Synalar; Fluonid; Flucinar

IUPAC/Chemical Name

(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one

InChl Key

FEBLZLNTKCEFIT-VSXGLTOVSA-N

InChl Code

InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/6215;

3D Conformer.

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