FLUNISOLIDE HEMIHYDRATE
Flunisolide is an inhaled corticosteroid reducing airway inflammation in asthma. Side effects include oral thrush, hoarseness, and throat irritation. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Flunisolide hemihydrate is an inhaled corticosteroid that binds glucocorticoid receptors to decrease airway inflammation, reduce cytokine release and improve respiratory function.
Benefits and Advantages
Used in asthma models, inhalationformulation research and airwayremodelling studies.
Side Effects and Risks
Possible oral candidiasis, hoarseness and adrenal suppression.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C24H31FO6·0.5H2O |
|---|---|
| Molecular Weight | 434.5 g/mol |
| CAS Number | 542449 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Practically insoluble |
| Purity | Purity information is available upon request (COA). |
| Synonym | flunisolide; 3385-03-3; Aerobid; Syntaris; Flunisolide anhydrous |
| IUPAC/Chemical Name | (1S,2S,4R,8S,9S,11S,12S,13R,19S)-19-fluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one |
| InChl Key | XSFJVAJPIHIPKU-XWCQMRHXSA-N |
| InChl Code | InChI=1S/C24H31FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h5-7,13-14,16-17,19-20,26,28H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1 |
| References |
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