FLUNARIZINE HCL

Flunarizine HCl is a calcium channel blocker used for migraine prevention. Side effects include drowsiness, weight gain, and depression. Only GMP materials will be supplied, logistics all according to GDP.

SKU: f222415597c9 Category: Tag:

Product Description


Mechanism of Action

Flunarizine HCl is a selective calciumchannel blocker with antihistaminic and antidopaminergic properties. It reduces neuronal excitability and vascular smoothmuscle tone.

Benefits and Advantages

Used in migrainepathway modelling, Ca²⁺ channel pharmacology, neurovascular research and CNS hyperexcitability studies.

Side Effects and Risks

Sedation, weight gain, depression and extrapyramidal symptoms may occur.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C26H26ClFN2·HCl

Molecular Weight

477.4 g/mol

CAS Number

30484-77-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

30484-77-6; flunarizine hydrochloride; Flunarizine HCl; Flunarizine (as hydrochloride); R 14950

IUPAC/Chemical Name

1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine;dihydrochloride

InChl Key

RXKMOPXNWTYEHI-RDRKJGRWSA-N

InChl Code

InChI=1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;;

References

https://pubchem.ncbi.nlm.nih.gov/compound/5282407;

3D Conformer.

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