FLUCONAZOLE

Fluconazole is a triazole antifungal inhibiting ergosterol synthesis. Side effects include headache, liver enzyme elevation, and GI upset. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 943f7186c52f Category: Tag:

Product Description


Mechanism of Action

Fluconazole is a triazole antifungal that inhibits 14demethylase (CYP51), blocking ergosterol synthesis and disrupting fungal cellmembrane structure.

Benefits and Advantages

Used in antifungal mechanism research, ergosterolpathway modelling and fungal growthinhibition assays.

Side Effects and Risks

Possible hepatic enzyme elevation, rash and QT prolongation.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C13H12F2N6O

Molecular Weight

306.27 g/mol

CAS Number

86386-73-4

Storage Condition

Fluconazole tablets should be stored in tight containers at a temperature less than 30 °C; fluconazole powder for oral suspension should be stored at a temperature less than 30 °C.

Solubility

slightly soluble in water

Purity

Purity information is available upon request (COA).

Synonym

fluconazole; 86386-73-4; Diflucan; Triflucan; Biozolene

IUPAC/Chemical Name

2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol

InChl Key

RFHAOTPXVQNOHP-UHFFFAOYSA-N

InChl Code

InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2

References

https://pubchem.ncbi.nlm.nih.gov/compound/3365;

3D Conformer.

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