FLUCONAZOLE
Fluconazole is a triazole antifungal inhibiting ergosterol synthesis. Side effects include headache, liver enzyme elevation, and GI upset.
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Product Description
Mechanism of Action
Fluconazole is a triazole antifungal that inhibits 14‑α‑demethylase (CYP51), blocking ergosterol synthesis and disrupting fungal cell‑membrane structure.
Benefits and Advantages
Used in antifungal mechanism research, ergosterol‑pathway modelling and fungal growth‑inhibition assays.
Side Effects and Risks
Possible hepatic enzyme elevation, rash and QT prolongation.
Datasheet
| Molecular Formula | C13H12F2N6O |
|---|---|
| Molecular Weight | 306.27 g/mol |
| CAS Number | 86386-73-4 |
| Storage Condition | Fluconazole tablets should be stored in tight containers at a temperature less than 30 °C; fluconazole powder for oral suspension should be stored at a temperature less than 30 °C. |
| Solubility | slightly soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | fluconazole; 86386-73-4; Diflucan; Triflucan; Biozolene |
| IUPAC/Chemical Name | 2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol |
| InChl Key | RFHAOTPXVQNOHP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2 |
| References |
3D Conformer.
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