FLOMOXEFUM

Flomoxef is an oxacephem antibiotic inhibiting bacterial cell wall synthesis. Side effects include rash, diarrhea, and elevated liver enzymes. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 57d1f511cca9 Category: Tag:

Product Description


Mechanism of Action

Flomoxef is an oxacephem lactam antibiotic that binds penicillinbinding proteins (PBPs), inhibiting transpeptidation of bacterial peptidoglycan. Its oxacephem core confers strong lactamase stability and broad Grampositive/Gramnegative activity.

Benefits and Advantages

Used in PBPprofiling studies, lactamase resistance modelling, and cellwall synthesis inhibition assays.

Side Effects and Risks

Potential GI upset, hypersensitivity, hepatic enzyme elevations and rare hematologic effects.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C15H18F2N6O7S2

Molecular Weight

496.5 g/mol

CAS Number

99665-00-6

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Flomoxef; 99665-00-6; Flomoxefum; FMOX; V9E5U5XF42

IUPAC/Chemical Name

(6R,7R)-7-[[2-(difluoromethylsulfanyl)acetyl]amino]-3-[[1-(2-hydroxyethyl)tetrazol-5-yl]sulfanylmethyl]-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

InChl Key

UHRBTBZOWWGKMK-DOMZBBRYSA-N

InChl Code

InChI=1S/C15H18F2N6O7S2/c1-29-15(18-8(25)6-31-13(16)17)11(28)23-9(10(26)27)7(4-30-12(15)23)5-32-14-19-20-21-22(14)2-3-24/h12-13,24H,2-6H2,1H3,(H,18,25)(H,26,27)/t12-,15+/m1/s1

References

https://pubchem.ncbi.nlm.nih.gov/compound/65864;

3D Conformer.

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