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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Product Description
Mechanism of Action
Fexofenadine HCl is a selective peripheral H1‑receptor antagonist. It blocks histamine‑induced vasodilation, edema and sensory‑nerve activation without crossing the blood–brain barrier.
Benefits and Advantages
Used in allergic disease models, H1‑receptor assays and histamine‑pathway pharmacology.
Side Effects and Risks
Generally well tolerated; possible headache, nausea or fatigue.
Datasheet
| Molecular Formula | C32H39NO4·HCl |
|---|---|
| Molecular Weight | 538.1 g/mol |
| CAS Number | 153439-40-8 |
| Storage Condition | Fexofenadine hydrochloride capsules, conventional tablets, and the extended-release tablets containing fexofenadine hydrochloride in fixed combination with pseudoephedrine hydrochloride should be stored at controlled room temperature between 20-25 °C; foil-backed blister packages containing the drug should be protected from excessive moisture. |
| Solubility | 71.8 [ug/mL] (The mean of the results at pH 7.4) |
| Purity | Purity information is available upon request (COA). |
| Synonym | FEXOFENADINE HYDROCHLORIDE; 153439-40-8; FEXOFENADINE HCL; Allegra Allergy; Allegra Hives |
| IUPAC/Chemical Name | 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid;hydrochloride |
| InChl Key | RRJFVPUCXDGFJB-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C32H39NO4.ClH/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27;/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36);1H |
| References |
3D Conformer.
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