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Product Description
Mechanism of Action
Etofylline clofibrate is a combined molecule of etofylline (bronchodilator) and clofibrate (PPAR‑α activator). The conjugate allows simultaneous modulation of lipid metabolism and improvement of respiratory airflow. Upon hydrolysis, each component exerts its own pharmacodynamic actions.
Benefits and Advantages
Used in dual‑mechanism prodrug research, PPAR‑α pathway assays, bronchodilation modelling, and lipid‑regulation studies.
Side Effects and Risks
Risks include tachycardia, hepatotoxicity, GI upset and hypersensitivity. Handle with fibrate‑xanthine dual‑agent precautions.
Datasheet
| Molecular Formula | C19H21ClN4O5 |
|---|---|
| Molecular Weight | 420.8 g/mol |
| CAS Number | 54504-70-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Etofylline clofibrate; 54504-70-0; THEOFIBRATE; Duolip; Etofyllinclofibrate |
| IUPAC/Chemical Name | 2-(1,3-dimethyl-2,6-dioxopurin-7-yl)ethyl 2-(4-chlorophenoxy)-2-methylpropanoate |
| InChl Key | KYAKGJDISSNVPZ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C19H21ClN4O5/c1-19(2,29-13-7-5-12(20)6-8-13)17(26)28-10-9-24-11-21-15-14(24)16(25)23(4)18(27)22(15)3/h5-8,11H,9-10H2,1-4H3 |
| References |
3D Conformer.
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