ETANIDAZOLE
Etanidazole is a radiosensitizer enhancing the effect of radiation therapy. Side effects include nausea, neuropathy, and headache.
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Product Description
Mechanism of Action
Etanidazole is a nitroimidazole radiosensitizer that enhances tumour sensitivity to ionizing radiation. Inside hypoxic cells, it undergoes reductive activation producing free radicals that damage DNA and interfere with repair pathways.
Benefits and Advantages
Used in radiobiology‑model systems, hypoxia‑targeted therapeutic research, DNA‑damage‑repair assays, and radiosensitization studies.
Side Effects and Risks
Risks include neuropathy, nausea, CNS effects and potential mutagenicity. Handle with nitroimidazole‑radiosensitizer precautions.
Datasheet
| Molecular Formula | C7H9N3O4S |
|---|---|
| Molecular Weight | 214.18 g/mol |
| CAS Number | 22668-01-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Water > 100 (mg/mL) |
| Purity | Purity information is available upon request (COA). |
| Synonym | etanidazole; 22668-01-5; Radinyl; Etanidazol; Etanidazolum |
| IUPAC/Chemical Name | N-(2-hydroxyethyl)-2-(2-nitroimidazol-1-yl)acetamide |
| InChl Key | WCDWBPCFGJXFJZ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C7H10N4O4/c12-4-2-8-6(13)5-10-3-1-9-7(10)11(14)15/h1,3,12H,2,4-5H2,(H,8,13) |
| References |
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