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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Product Description
Mechanism of Action
Esomeprazole is the S‑isomer of omeprazole and a proton‑pump inhibitor that irreversibly inhibits the H⁺/K⁺‑ATPase pump on gastric parietal cells. This suppresses basal and stimulated gastric acid secretion. The magnesium salt enhances stability and absorption.
Benefits and Advantages
Used in gastric‑acid secretion research, proton‑pump inhibition modelling, enantiomer‑selective PK/PD studies, and gastrointestinal mucosal protection assays.
Side Effects and Risks
Risks include hypomagnesemia, B12 deficiency, increased fracture risk (long term) and rare renal injury. Handle with PPI‑class precautions.
Datasheet
| Molecular Formula | C34H36N6O6S2Mg |
|---|---|
| Molecular Weight | 713.1 g/mol |
| CAS Number | 161973-10-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Esomeprazole magnesium; Nexium 24hr; 925R0D7W1O; CHEBI:50309; DTXSID5044231 |
| IUPAC/Chemical Name | magnesium bis(5-methoxy-2-[(S)-(4-methoxy-3,5-dimethyl-2-pyridinyl)methylsulfinyl]benzimidazol-1-ide) |
| InChl Key | KWORUUGOSLYAGD-YPPDDXJESA-N |
| InChl Code | InChI=1S/2C17H18N3O3S.Mg/c2*1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h2*5-8H,9H2,1-4H3;/q2*-1;+2/t2*24-;/m00./s1 |
| References |
3D Conformer.
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