ERDOSTEINE
Erdosteine is a mucolytic enhancing mucous clearance and reducing inflammation in respiratory diseases. Side effects include nausea, rash, and mild GI upset. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Erdosteine is a thiolreleasing mucolytic prodrug. After hepatic metabolism, it generates free sulfhydryl groups that disrupt disulfide bonds in mucin glycoproteins, lowering sputum viscosity. It also exhibits antioxidant activity by scavenging reactive oxygen species and modulating inflammatory mediators in the respiratory tract.
Benefits and Advantages
Used in airwaymucus viscosity studies, antioxidantinlung research, COPD and bronchitis modelling, and thiolprodrug activation assays.
Side Effects and Risks
Risks include nausea, dyspepsia, rare skin eruptions and transient increases in liver enzymes. Handle with thiolcontaining mucolytic precautions.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C8H15NO4S2 |
|---|---|
| Molecular Weight | 249.3 g/mol |
| CAS Number | 84611-23-4 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Erdosteine; 84611-23-4; RV-144; Erdosteinum; Mucotec |
| IUPAC/Chemical Name | 2-[2-oxo-2-[(2-oxothiolan-3-yl)amino]ethyl]sulfanylacetic acid |
| InChl Key | QGFORSXNKQLDNO-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C8H11NO4S2/c10-6(3-14-4-7(11)12)9-5-1-2-15-8(5)13/h5H,1-4H2,(H,9,10)(H,11,12) |
| References |
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