EDTA CALCIUM DISODIUM

EDTA calcium disodium is a chelator used in lead poisoning to bind and promote excretion of heavy metals. Side effects include fever, nephrotoxicity, and local discomfort with injection. Only GMP materials will be supplied, logistics all according to GDP.

SKU: 47e3b9ea0f38 Category: Tag:

Product Description


Mechanism of Action

Calcium disodium EDTA is a chelating compound designed to preferentially bind heavy metals (lead, cadmium) without inducing hypocalcemia. The preloaded calcium ion reduces the risk of binding endogenous Ca²⁺ while still allowing exchange with toxic metals. It forms highly stable complexes excreted renally.

Benefits and Advantages

Used in heavymetal detoxification modelling, chelationefficiency assays, toxicology research, and metalion exchange studies.

Side Effects and Risks

Risks include nephrotoxicity, local pain (in injections), GI upset and rare mineralimbalance disturbances. Handle with chelationtherapy precautions.

Only GMP materials will be supplied, logistics all according to GDP.

Datasheet


Molecular Formula

C10H12CaN2Na2O8

Molecular Weight

374.27 g/mol

CAS Number

62-33-9

Storage Condition

Edetate calcium disodium injection should be stored at controlled room temperature (15-30 °C).

Solubility

Powder. Solubility in water: at 20 °C a 0.1M solution can be prepared (pH approx 7). Pratically insoluble in organic solvents /Tetrahydrate/

Purity

Purity information is available upon request (COA).

Synonym

Edetate calcium disodium; EDTA calcium disodium; Detoxamin; Edetate calcium disodium anhydrous; Calcium disodium ethylenediaminetetraacetate

IUPAC/Chemical Name

calcium;disodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate

InChl Key

SHWNNYZBHZIQQV-UHFFFAOYSA-J

InChl Code

InChI=1S/C10H16N2O8.Ca.2Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;/q;+2;2*+1/p-4

References

https://pubchem.ncbi.nlm.nih.gov/compound/6093170;

3D Conformer.

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