ECONAZOLE BASE
Econazole base is an imidazole antifungal that disrupts ergosterol synthesis in fungal cell membranes. It is effective against dermatophytes and yeasts. Side effects include mild burning, redness, or irritation at the application site.
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Product Description
Mechanism of Action
Econazole is an imidazole antifungal that inhibits fungal cytochrome P450‑dependent 14‑α‑demethylase, blocking conversion of lanosterol to ergosterol. This disrupts cell‑membrane synthesis, increasing permeability and causing fungal death. It is active against dermatophytes, yeasts and some molds.
Benefits and Advantages
Used in fungal‑cell‑membrane research, azole‑mechanism assays, ergosterol‑biosynthesis modelling, and antifungal‑resistance studies.
Side Effects and Risks
Risks include local irritation, burning, erythema, contact dermatitis and rare systemic absorption effects. Handle with azole‑antifungal precautions.
Datasheet
| Molecular Formula | C18H15Cl3N2O |
|---|---|
| Molecular Weight | 381.68 g/mol |
| CAS Number | 27220-47-9 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | econazole; 27220-47-9; Econazolum; Econazol; (+-)-Econazole |
| IUPAC/Chemical Name | 1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanol |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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