DIFEMERINE

Difemerine is an anticholinergic antispasmodic used for gastrointestinal discomfort. Side effects include dry mouth, blurred vision, and sedation.

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Product Description


Mechanism of Action

Difemerine is an antispasmodic and anticholinergic agent that inhibits M‑receptor‑mediated smooth‑muscle contraction, particularly in the gastrointestinal and urinary tracts. It reduces visceral pain by decreasing motility and muscle tone.

Benefits and Advantages

Used in smooth‑muscle research, parasympathetic‑inhibition studies, antispasmodic SAR analysis, and GI motility modelling.

Side Effects and Risks

Risks include anticholinergic effects: dry mouth, blurred vision, constipation, urinary retention and tachycardia. Handle with antimuscarinic‑agent precautions.

Datasheet


Molecular Formula

C20H25NO2

Molecular Weight

327.4 g/mol

CAS Number

80387-96-8

Storage Condition

Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light.

Solubility

Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance.

Purity

Purity information is available upon request (COA).

Synonym

Difemerine; 80387-96-8; Difemerinum; 843C4UPZ2F; 2-(Dimethylamino)-1,1-dimethylethyl benzilate

IUPAC/Chemical Name

[2-(dimethylamino)-2-methylpropyl] 2-hydroxy-2,2-diphenylacetate

InChl Key

GUONSMXZEYTWML-UHFFFAOYSA-N

InChl Code

InChI=1S/C20H25NO3/c1-19(2,21(3)4)15-24-18(22)20(23,16-11-7-5-8-12-16)17-13-9-6-10-14-17/h5-14,23H,15H2,1-4H3

References

https://pubchem.ncbi.nlm.nih.gov/compound/165124;

3D Conformer.

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