DERMATAN SULFATE
Dermatan sulfate is a glycosaminoglycan involved in coagulation and wound repair, interacting with heparin cofactor II to inhibit thrombin. Benefits include improved tissue healing and antithrombotic effects. Side effects may include bleeding tendencies or hypersensitivity reactions in therapeutic or . Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
Dermatan sulfate is a glycosaminoglycan (GAG) composed of repeating Liduronic acid and NacetylDgalactosamine units. It binds growth factors, cytokines and extracellular matrix proteins, influencing wound healing, coagulation and fibrosis. It also interacts with heparin cofactor II, enhancing thrombin inhibition.
Benefits and Advantages
Used in extracellularmatrix research, GAGbinding assays, regenerativemedicine studies, coagulationpathway modelling, and fibrosisrelated investigations.
Side Effects and Risks
Risks include anticoagulant effects, allergic reactions, contaminationrelated concerns and variability in biological activity. Handle as a biologically active polysaccharide.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C14H21NO15S-2 |
|---|---|
| Molecular Weight | 475.4 g/mol |
| CAS Number | 24967-94-0 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | DERMATAN SULFATE; Chondroitin sulfate B; beta-Heparin; Dermatan sulphate; Dermatan hydrogen sulfate |
| IUPAC/Chemical Name | (2R,3S,4S,5R,6R)-6-[(2R,3R,4R,5R,6R)-3-acetamido-2-hydroxy-6-(hydroxymethyl)-5-sulfonatooxyoxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate |
| InChl Key | AVJBPWGFOQAPRH-FWMKGIEWSA-L |
| InChl Code | InChI=1S/C14H23NO15S/c1-3(17)15-5-10(9(30-31(24,25)26)4(2-16)27-13(5)23)28-14-8(20)6(18)7(19)11(29-14)12(21)22/h4-11,13-14,16,18-20,23H,2H2,1H3,(H,15,17)(H,21,22)(H,24,25,26)/p-2/t4-,5-,6+,7+,8-,9+,10-,11-,13-,14-/m1/s1 |
| References |
3D Conformer.
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