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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cyclopenthiazide is a thiazide diuretic that inhibits the Na⁺/Cl cotransporter (NCC) in the distal convoluted tubule, increasing excretion of sodium, chloride and water. It also reduces calcium excretion and lowers peripheral vascular resistance with chronic exposure.
Benefits and Advantages
Used in renalelectrolyte transport studies, NCCinhibition assays, antihypertensivemechanism modelling, and fluidbalance research.
Side Effects and Risks
Risks include hypokalemia, hyponatremia, hyperuricemia, glucose intolerance and hypotension. Handle under diureticclass safety controls.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C14H20ClN3O4S2 |
|---|---|
| Molecular Weight | 379.9 g/mol |
| CAS Number | 742-20-1 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | cyclopenthiazide; 742-20-1; Cyclomethiazide; Navidrex; Ciclopentiazida |
| IUPAC/Chemical Name | 6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide |
| InChl Key | BKYKPTRYDKTTJY-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C13H18ClN3O4S2/c14-9-6-10-12(7-11(9)22(15,18)19)23(20,21)17-13(16-10)5-8-3-1-2-4-8/h6-8,13,16-17H,1-5H2,(H2,15,18,19) |
| References |
3D Conformer.
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