About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cloperastine is a centrally acting antitussive with antihistaminic and anticholinergic properties. It modulates the cough reflex by reducing medullary excitability and stabilizing sensory nerve fibres. It also exhibits mild calcium‑channel blocking activity.
Benefits and Advantages
Used in cough‑reflex modelling, airway‑sensory neuron research, calcium‑channel interaction studies and histamine‑modulation assays.
Side Effects and Risks
Risks include drowsiness, dizziness, mild anticholinergic effects and rare hypersensitivity. Handle as a CNS‑active antitussive compound.
Datasheet
| Molecular Formula | C19H23ClNO3 |
|---|---|
| Molecular Weight | 329.9 g/mol |
| CAS Number | 3703-76-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | cloperastine; 3703-76-2; Cloperastina; Cloperastinum; HT-11 |
| IUPAC/Chemical Name | 1-[2-[(4-chlorophenyl)-phenylmethoxy]ethyl]piperidine |
| InChl Key | FLNXBVJLPJNOSI-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H24ClNO/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22/h1,3-4,7-12,20H,2,5-6,13-16H2 |
| References |
3D Conformer.
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