CITALOPRAM OXALATE
Citalopram oxalate is the salt form of citalopram with identical SSRI activity, improving serotonin transmission. Benefits include reduced depressive symptoms. Side effects include dizziness, dry mouth, and sleep disturbances.
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Product Description
Mechanism of Action
Citalopram oxalate is the salt form commonly used in pharmaceutical formulations. Mechanism identical: potent inhibition of the serotonin transporter (SERT), increasing extracellular serotonin and enhancing serotonergic signalling. The oxalate form offers improved stability and solubility.
Benefits and Advantages
Used in formulation-stability research, SSRI pharmacokinetic studies, SERT-inhibition assays and salt-optimization comparisons.
Side Effects and Risks
Risks mirror citalopram: QT interval prolongation, CNS effects, GI disturbances, serotonin syndrome and withdrawal phenomena. Handle as an SSRI-class compound.
Datasheet
| Molecular Formula | C22H23FN2O5 |
|---|---|
| Molecular Weight | 414.4 g/mol |
| CAS Number | 207559-01-1 |
| Storage Condition | Store at 20 °C to 25 °C (68 °F to 77 °F); excursions permitted from 15 °C to 30 °C (59 °F to 86 °F). |
| Solubility | Sparingly soluble |
| Purity | Purity information is available upon request (COA). |
| Synonym | Citalopram Oxalate; 207559-01-1; B5RDX2419X; UNII-B5RDX2419X; 5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, ethanedioate (1:1) |
| IUPAC/Chemical Name | 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile;oxalic acid |
| InChl Key | KTGRHKOEFSJQNS-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C20H21FN2O.C2H2O4/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;3-1(4)2(5)6/h4-9,12H,3,10-11,14H2,1-2H3;(H,3,4)(H,5,6) |
| References |
3D Conformer.
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