CITALOPRAM OXALATE

Citalopram oxalate is the salt form of citalopram with identical SSRI activity, improving serotonin transmission. Benefits include reduced depressive symptoms. Side effects include dizziness, dry mouth, and sleep disturbances.

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Product Description


Mechanism of Action

Citalopram oxalate is the salt form commonly used in pharmaceutical formulations. Mechanism identical: potent inhibition of the serotonin transporter (SERT), increasing extracellular serotonin and enhancing serotonergic signalling. The oxalate form offers improved stability and solubility.

Benefits and Advantages

Used in formulation-stability research, SSRI pharmacokinetic studies, SERT-inhibition assays and salt-optimization comparisons.

Side Effects and Risks

Risks mirror citalopram: QT interval prolongation, CNS effects, GI disturbances, serotonin syndrome and withdrawal phenomena. Handle as an SSRI-class compound.

Datasheet


Molecular Formula

C22H23FN2O5

Molecular Weight

414.4 g/mol

CAS Number

207559-01-1

Storage Condition

Store at 20 °C to 25 °C (68 °F to 77 °F); excursions permitted from 15 °C to 30 °C (59 °F to 86 °F).

Solubility

Sparingly soluble

Purity

Purity information is available upon request (COA).

Synonym

Citalopram Oxalate; 207559-01-1; B5RDX2419X; UNII-B5RDX2419X; 5-Isobenzofurancarbonitrile, 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydro-, ethanedioate (1:1)

IUPAC/Chemical Name

1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile;oxalic acid

InChl Key

KTGRHKOEFSJQNS-UHFFFAOYSA-N

InChl Code

InChI=1S/C20H21FN2O.C2H2O4/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;3-1(4)2(5)6/h4-9,12H,3,10-11,14H2,1-2H3;(H,3,4)(H,5,6)

References

https://pubchem.ncbi.nlm.nih.gov/compound/21871605;

3D Conformer.

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