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Product Description
Mechanism of Action
Cimetidine base is the non‑salt form of cimetidine with identical H₂‑receptor antagonism. It competitively blocks histamine‑driven gastric acid secretion and possesses significant CYP450‑inhibitory activity. The base form is used in formulation chemistry and lipophilicity studies.
Benefits and Advantages
Used in pharmaceutical‑salt comparison studies, solubility testing, H₂‑receptor mechanism modelling, CYP‑interaction assays and medicinal‑chemistry optimisation experiments.
Side Effects and Risks
Risks mirror standard cimetidine: hormone‑disruption effects, CNS alterations, hepatic changes and major drug‑interaction potential. Handle with H₂‑antagonist precautions.
Datasheet
| Molecular Formula | C10H16N6S |
|---|---|
| Molecular Weight | 252.34 g/mol |
| CAS Number | 51481-61-9 |
| Storage Condition | Store in a cool, dry place; protect from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| Synonym | cimetidine; 51481-61-9; Ulcedin; Eureceptor; Gastromet |
| IUPAC/Chemical Name | N''-cyano-N-methyl-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]guanidine |
| InChl Key | Unavailable |
| InChl Code | Unavailable |
| References | PubChem; ChemBL; FDA; |
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