CHLORPROMAZINE HCL
Chlorpromazine HCl is a phenothiazine antipsychotic blocking dopamine D2 receptors, used for schizophrenia, agitation, and nausea. Side effects include sedation, hypotension, anticholinergic effects, EPS, and photosensitivity. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Mechanism of Action
CHLORPROMAZINE HCL demonstrates a highdimensional biochemical activity framework integrating catalyticdomain modulation, multiaxis signalling interference, mitochondrialnetwork recalibration, redoxequilibrium restructuring, ionflux redistribution, membranepotential modulation, cytoskeletalarchitecture remodelling and transcriptionfactor circuit reprogramming. The compounds molecular topology supports interaction with catalytic residues, allosteric microdomains, transmembrane helices, nucleotidebinding pockets, redoxbuffer matrices and polymeric scaffolding complexesenabling influence across metabolic, genomic, structural and electrophysiological systems.
CHLORPROMAZINE HCL may alter phosphorylationflow geometry across ERK, MAPK, JNK, p38 and PI3KAKT axes; reconfigure Gprotein signalstate logic; redistribute Ca²⁺ microdomains; adjust IP/DAG signalling topology; and recalibrate cAMPPKA amplitude. Mitochondrial effects include ETCcomplex rebalancing, ATP/ADP flux modulation, ROSthreshold displacement, membranepotential polarity shifting, and ERmitochondria stresssignal crosstalk integration.
HighPrecision
- Kinomescale interference mapping & catalyticcascade modelling
- Highresolution molecular docking & conformationaltransition prediction
- UPR/ERstress, mitophagy & autophagicflux regulatory modelling
- Multiomics network reconstruction: RNAseq, metabolomics, proteomics, phosphoproteomics
- Cytoskeletal tensionmapping & polymerturnover analytics
- Advanced cellfate pathway modelling (apoptosis, necroptosis, ferroptosis, parthanatos)
- AIdriven SAR/QSAR predictive compoundperformance optimisation
Toxicodynamics & Hazard Spectrum
- Rapid ROS escalation & antioxidantbuffer collapse
- Mitochondrial fragmentation or ETCaxis suppression
- Severe Na⁺/K⁺/Ca²⁺ ionic-flux destabilisation
- Cytoskeletal depolymerisation & membrane-integrity loss
- Inflammatory hyperactivation (NF-κB, STAT, IRF signalling clusters)
- Activation of multiaxis programmed-cell-death pathways
- Epigenetic drift including methylation/acetylation instability
For expert not intended for biological or therapeutic exposure.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C17H20Cl2N2S |
|---|---|
| Molecular Weight | 355.3 g/mol |
| CAS Number | 69-09-0 |
| Storage Condition | Chlorpromazine hydrochloride oral solutions, tablets, and injection should be stored at a temperature less than 40 °C, preferably between 15-30 °C; freezing of the oral solutions and injection should be avoided. … Chlorpromazine suppositories should be stored in well-closed containers between 15-30 °C. …Chlorpromazine hydrochloride oral concentrate solution should be dispensed in amber glass bottles. |
| Solubility | greater than or equal to 100 mg/mL at 75 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Chlorpromazine hydrochloride; 69-09-0; Chlorpromazine Hcl; Sonazine; Chloractil |
| IUPAC/Chemical Name | 3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine;hydrochloride |
| InChl Key | FBSMERQALIEGJT-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H |
| References |
3D Conformer.
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