About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Chloroquine phosphate is a widely used salt form of chloroquine providing stable aqueous solubility. It accumulates in parasite vacuoles and mammalian lysosomes, impairing heme‑polymerisation, altering autophagic flux, and interfering with TLR‑mediated immune signalling. Also used to block viral entry via endosomal pH elevation.
Benefits and Advantages
Used in parasite‑metabolism modelling, host‑pathogen interaction research, autophagy and lysosome‑dysfunction studies, toll‑like receptor pathway analysis and antiviral‑screening platforms.
Side Effects and Risks
Risks include retinopathy, cardiotoxicity, neuropsychiatric effects, GI symptoms and hepatic stress. Handle with high‑safety controls due to systemic toxicity.
Datasheet
| Molecular Formula | C18H32ClN3O8P2 |
|---|---|
| Molecular Weight | 515.9 g/mol |
| CAS Number | 1688677-89-5 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Chloroquine diphosphate; Chloroquine phosphate; Arechin; Avloclor; Resochin |
| IUPAC/Chemical Name | 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine;phosphoric acid |
| InChl Key | QKICWELGRMTQCR-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4) |
| References |
3D Conformer.
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