About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
Cenfloxacin is a synthetic fluoroquinolone antibacterial that inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV—enzymes required for supercoiling, replication, transcription, and segregation of bacterial DNA. By stabilizing the DNA–enzyme cleavage complex, cenfloxacin induces lethal double‑strand breaks in replicating bacterial cells, leading to rapid bactericidal activity, especially against gram‑negative organisms.
Benefits and Advantages
Used in quinolone-resistance modelling, gyrase-target structural studies, bacterial DNA-replication assays, gram‑negative susceptibility research, PK/PD optimisation simulations, and fluoroquinolone SAR investigations. Helpful for studying quinolone binding pockets, QRDR mutations, and efflux‑pump–mediated resistance.
Side Effects and Risks
Risks include phototoxicity, QT prolongation, tendon injury, CNS stimulation (seizure risk), dysbiosis, and hepatotoxicity. Handle with strict antibacterial‑compound precautions.
Datasheet
| Molecular Formula | C17H19FN2O2 |
|---|---|
| Molecular Weight | 302.35 g/mol |
| CAS Number | 55987-18-7 |
| Storage Condition | Store in a cool, dry place; protected from light |
| Solubility | Soluble in water |
| Purity | Purity information is available upon request (COA). |
| IUPAC/Chemical Name | 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(pyrrolidin-1-ylmethyl)quinoline-3-carboxylic acid |
| InChl Key | OIWPHESVZQYNPB-UHFFFAOYSA-N |
| References | PubChem; ChemBL; FDA substance registry; |
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