BUTAMBEN
Butamben is a surface anesthetic used for mucosal procedures. Benefits include stable, localized anesthesia. Side effects include sensitization and irritation.
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Product Description
Mechanism of action
Butamben is a lipophilic ester local anaesthetic that inhibits voltage-gated sodium channels in sensory nerves, producing surface-level and mucosal anaesthesia. Its high hydrophobicity allows prolonged receptor occupancy and sustained analgesia. It is commonly used in combination with other anaesthetics to extend local effect.
Benefits and advantages
Used in topical-anaesthesia research, sodium-channel modulation studies, dermal-penetration modelling, multi-agent anaesthetic formulation testing and peripheral nerve blockade experiments.
Side effects and risks
Risks include methemoglobinemia (rare), allergic reactions typical of ester anaesthetics, CNS toxicity at high exposure and local irritation. Employ topical-anaesthetic safety protocols.
Datasheet
| Molecular Formula | C17H27NO2 |
|---|---|
| Molecular Weight | 193.24 g/mol |
| CAS Number | 94-25-7 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Insoluble (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Butyl 4-aminobenzoate; butamben; 94-25-7; Butoform; Butyl aminobenzoate |
| IUPAC/Chemical Name | butyl 4-aminobenzoate |
| InChl Key | IUWVALYLNVXWKX-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C11H15NO2/c1-2-3-8-14-11(13)9-4-6-10(12)7-5-9/h4-7H,2-3,8,12H2,1H3 |
| References |
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