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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Product Description
Mechanism of action
Bepridil is a unique non-selective calcium-channel blocker that inhibits L-, T-, and N-type calcium channels, while also blocking sodium and potassium channels, giving it a broad electrophysiological footprint. The drug prolongs cardiac action potential duration and slows conduction, reducing myocardial oxygen demand and modifying arrhythmic activity.
Benefits and advantages
Highly valuable in electrophysiology research, ion-channel pharmacology, arrhythmia modelling, QT-prolongation studies and comparative multichannel-inhibitor testing. Bepridil is especially important in investigations of early afterdepolarisations and torsadogenic risk.
Side effects and risks
Risks include QT prolongation, torsades de pointes, hypotension, dizziness, and conduction block. Handle only under cardiac-active compound precautions with avoidance of inhalation or contamination.
Datasheet
| Molecular Formula | C24H34N2O |
|---|---|
| Molecular Weight | 366.5 g/mol |
| CAS Number | 64706-54-3 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Slightly soluble |
| Purity | Purity information is available upon request (COA). |
| Synonym | bepridil; 64706-54-3; DTXSID3022663; 755BO701MA; N-benzyl-N-[3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl]aniline |
| IUPAC/Chemical Name | N-benzyl-N-[3-(2-methylpropoxy)-2-pyrrolidin-1-ylpropyl]aniline |
| InChl Key | UIEATEWHFDRYRU-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C24H34N2O/c1-21(2)19-27-20-24(25-15-9-10-16-25)18-26(23-13-7-4-8-14-23)17-22-11-5-3-6-12-22/h3-8,11-14,21,24H,9-10,15-20H2,1-2H3 |
| References |
3D Conformer.
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