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MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
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Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
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Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of action
Aminopyrin inhibits COX enzymes to reduce prostaglandin production, mediating analgesic and antipyretic effects. More importantly, its metabolism to reactive intermediates such as 4‑aminoantipyrine accounts for its historical toxicity and relevance in pharmacokinetic probe studies.
Benefits and advantages
Still used in the aminopyrine breath test to measure hepatic demethylation capacity and microsomal oxidative function. Highly valuable in hepatology research.
Side effects and risks
Agranulocytosis, hepatic necrosis, hypersensitivity, shock-like reactions. Requires strict PPE and dedicated ventilation.
Datasheet
| Molecular Formula | C13H17N3O |
|---|---|
| Molecular Weight | 231.29 g/mol |
| CAS Number | 58-15-1 |
| Storage Condition | …MATERIALS WHICH…CAN DECOMP INTO TOXIC COMPONENTS DUE TO CONTACT WITH HEAT…STORED IN COOL, WELL-VENTILATED PLACE, OUT OF…RAYS OF SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD…PERIODICALLY INSPECTED & MONITORED. INCOMPATIBLE MATERIALS…ISOLATED FROM EACH OTHER. |
| Solubility | greater than or equal to 100 mg/mL at 72 °F (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | aminophenazone; AMINOPYRINE; Amidopyrine; 58-15-1; 4-Dimethylaminoantipyrine |
| IUPAC/Chemical Name | 4-(dimethylamino)-1,5-dimethyl-2-phenylpyrazol-3-one |
| InChl Key | RMMXTBMQSGEXHJ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C13H17N3O/c1-10-12(14(2)3)13(17)16(15(10)4)11-8-6-5-7-9-11/h5-9H,1-4H3 |
| References |
3D Conformer.
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