ADRENALINE HYDROCHLORIDE
Adrenaline hydrochloride is a stabilized form of epinephrine used in injectable preparations for severe allergic reactions and cardiac arrest. It acts via α‑ and β‑receptors to restore perfusion and airway patency. Benefits include rapid response and high efficacy. Side effects include tremors, sweating, tachycardia, and potentially dangerous arrhythmias.
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Product Description
Mechanism of action
Adrenaline hydrochloride is a water‑soluble salt form of epinephrine suitable for injectable and topical preparations. It retains the full spectrum of adrenergic agonist activity, stimulating alpha‑ and beta‑adrenergic receptors to produce vasoconstriction, increased cardiac output and bronchodilation.
Benefits and advantages
The hydrochloride salt provides good aqueous solubility and stability for parenteral use. It is widely employed in emergency kits for anaphylaxis, advanced cardiac life support algorithms and as an adjunct to local anaesthetics to reduce systemic absorption and prolong duration of action.
Side effects and risks
Risks are identical to those of other adrenaline preparations: tachyarrhythmias, hypertension, myocardial ischaemia, anxiety and tremor, particularly at higher doses or in susceptible patients. Manufacturing and handling require controls to limit oxidation and ensure accurate dosing.
Professional use only. Supplied exclusively to licensed manufacturers and healthcare institutions.
Datasheet
| Molecular Formula | C9H14ClNO3 |
|---|---|
| Molecular Weight | 219.66 g/mol |
| CAS Number | 55-31-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Sparingly soluble (NTP, 1992) |
| Purity | Purity information is available upon request (COA). |
| Synonym | Epinephrine hydrochloride; 55-31-2; Epinephrine HCl; Adrenaline hydrochloride; Adrenalin chloride |
| IUPAC/Chemical Name | 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride |
| InChl Key | ATADHKWKHYVBTJ-FVGYRXGTSA-N |
| InChl Code | InChI=1S/C9H13NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,9-13H,5H2,1H3;1H/t9-;/m0./s1 |
| References |
3D Conformer.
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