ADAMANTANE
Adamantane is a tricyclic hydrocarbon framework used as a structural base in antiviral and antiparkinsonian drugs such as amantadine. Its mechanism involves modulation of NMDA receptors and inhibition of viral uncoating in influenza A. Benefits include enhanced drug stability and activity. Side effects may include dizziness, insomnia, nausea, and confusion, depending on the derivative compound.
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Product Description
Mechanism of action
Adamantane is a rigid tricyclic hydrocarbon that serves primarily as a structural scaffold. Derivatives of adamantane, such as amantadine and rimantadine, possess antiviral and antiparkinsonian activity, but unsubstituted adamantane itself is mainly used as an intermediate in the synthesis of pharmaceuticals and advanced materials.
Benefits and advantages
The unique cage‑like structure of adamantane imparts exceptional stability and lipophilicity, making it a valuable building block for drug design and for modifying the physicochemical properties of active molecules. It is also used in polymer and coating technologies to enhance durability and thermal resistance.
Side effects and risks
Adamantane has low intrinsic biological activity, but derivatives may be pharmacologically potent. As a hydrophobic organic solid, it should be handled with routine industrial hygiene measures to prevent dust inhalation or environmental contamination. Any use in drug synthesis must comply with applicable regulatory standards.
Professional use only. Supplied exclusively to licensed companies and research institutions.
Datasheet
| Molecular Formula | C10H16 |
|---|---|
| Molecular Weight | 136.23 g/mol |
| CAS Number | 281-23-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | ADAMANTANE; 281-23-2; Tricyclo[3.3.1.13,7]decane; Tricyclo[3.3.1.1(3,7)]decane; Tricyclo(3.3.1.13,7)decane |
| IUPAC/Chemical Name | adamantane |
| InChl Key | ORILYTVJVMAKLC-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C10H16/c1-7-2-9-4-8(1)5-10(3-7)6-9/h7-10H,1-6H2 |
| References |
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