NERATINIB MALATE
Neratinib Malate is a research-grade compound used in advanced pharmaceutical and biochemical studies. Chemical & Pharmacological Characteristics Behavior in experimental systems is governed by solubility, stability, ionization state, and matrix interactions. Controlled formulation is essential. Mechanism of Action No single receptor-driven mechanism is assumed; observed effects are concentration- and context-dependent. It is primarily applied to investigate compound-specific mechanisms, physicochemical behavior, and analytical or formulation-relevant characteristics under controlled laboratory conditions. Only GMP materials will be supplied, logistics all according to GDP.
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Product Description
Chemical & Pharmacological Characteristics
Behavior in experimental systems is governed by solubility, stability, ionization state, and matrix interactions. Controlled formulation is essential.
Mechanism of Action
No single receptor-driven mechanism is assumed; observed effects are concentration- and context-dependent.
Interpretation should include matched controls to separate direct chemical effects from secondary stress responses.
Advanced
- Analytical reference and quality control
- Formulation development and stability screening
- Compatibility testing with excipients and packaging
- Comparative toxicology benchmarking
- Documentation support for R&D workflows
Toxicodynamics & Cellular Hazard Spectrum
- Nonspecific cytotoxicity at high exposure
- Solubility or aggregation artifacts
- Matrix-dependent assay interference
- Handling-related irritation risk
- Dispose according to laboratory waste regulations
For expert laboratory research only – not intended for biological or therapeutic exposure.
Only GMP materials will be supplied, logistics all according to GDP.
Datasheet
| Molecular Formula | C34H33ClN6O7 |
|---|---|
| Molecular Weight | 673.1 g/mol |
| CAS Number | 915942-22-2 |
| Storage Condition | Store in a cool, dry place. Keep container tightly closed. Protect from moisture and light. |
| Solubility | Solubility depends on solvent and conditions (e.g., pH). Please contact us for solvent-specific guidance. |
| Purity | Purity information is available upon request (COA). |
| Synonym | Neratinib maleate; 915942-22-2; hki-272 maleate; 9RM7XY23ZS; NERATINIB MALEATE ANHYDROUS |
| IUPAC/Chemical Name | (Z)-but-2-enedioic acid;(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide |
| InChl Key | VXZCUHNJXSIJIM-MEBGWEOYSA-N |
| InChl Code | InChI=1S/C30H29ClN6O3.C4H4O4/c1-4-39-28-16-25-23(15-26(28)36-29(38)9-7-13-37(2)3)30(20(17-32)18-34-25)35-21-10-11-27(24(31)14-21)40-19-22-8-5-6-12-33-22;5-3(6)1-2-4(7)8/h5-12,14-16,18H,4,13,19H2,1-3H3,(H,34,35)(H,36,38);1-2H,(H,5,6)(H,7,8)/b9-7+;2-1- |
| References | small-molecule |
3D Conformer.
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