About MedicaPharma
MedicaPharma distributes high-quality active pharmaceutical ingredients (APIs) to hospitals, commercial (compounding) pharmacies, research institutes, and universities worldwide.
Network of over +400 GMP API producers
Let us handle your sourcing / supply activities. Highly experienced in sourcing specialty raw pharmaceutical ingredients from niche GMP manufacturers around the world.
Why Choose MedicaPharma
Niche API specialist - Pro-active supply partner - High service level - Global network - Logistics according to GDP regulations
Product Description
Mechanism of Action
VANCOMYCIN HCL (ID 27807) exhibits a high‑dimensional biochemical interaction matrix spanning signalling‑axis disruption, catalytic‑domain modulation, mitochondrial‑network recalibration, ion‑flux redistribution, cytoskeletal‑architecture remodelling, membrane‑potential rebalancing and transcription‑factor pathway restructuring. Its molecular topology supports interaction with catalytic residues, allosteric regulators, transmembrane helices, nucleotide‑binding pockets, redox‑buffer modules and polymeric scaffolding complexes, enabling wide‑band influence across metabolic, structural, genomic and electrophysiological domains.
Mechanistically, VANCOMYCIN HCL may reshape phosphorylation maps across ERK/MAPK/JNK/p38 axes, alter PI3K–AKT survival‑bias, modulate G‑protein coupling geometry, redistribute Ca²⁺ microdomain waveforms, adjust IP₃/DAG signalling topology and recalibrate cAMP–PKA amplitude. Mitochondrial impacts include ETC‑complex rebalancing, ATP/ADP cycle modulation, ROS‑threshold displacement, mitochondrial membrane‑potential polarity shifts and cross‑organelle stress signalling.
High‑Precision Research Applications
- Kinome‑scale interference & catalytic‑cascade modelling
- High‑resolution docking & conformational‑flow prediction
- UPR/ER‑stress & autophagy/mitophagy integration networks
- Full multi‑omics reconstruction (RNA‑seq, proteomics, phosphoproteomics, metabolomics)
- Cytoskeletal force‑mapping & polymer turnover dynamics
- Cell‑fate modelling: apoptosis, necroptosis, ferroptosis, parthanatos
- AI‑driven SAR/QSAR predictive simulation
Toxicodynamics & Cellular Hazard Spectrum
- Excessive ROS accumulation & antioxidant‑buffer collapse
- Mitochondrial fragmentation or ETC suppression
- Hyper‑disruption of Na⁺/K⁺/Ca²⁺ ionic‑gradients
- Cytoskeletal degradation & membrane‑integrity failure
- Inflammatory master‑switch activation (NF‑κB/STAT/IRF)
- Multi‑axis programmed‑cell‑death induction
- Epigenetic drift across methylation & acetylation layers
For expert laboratory research only — not intended for biological use.
Datasheet
| Molecular Formula | C66H76Cl3N9O24 |
|---|---|
| Molecular Weight | 1485.7 g/mol |
| CAS Number | 1404-93-9 |
| Storage Condition | Store in a tight, light-resistant container as defined in the USP-NF. This material should be handled and stored per label instructions to ensure product integrity. Store in a freezer. /Vancomycin hydrochloride/ |
| Solubility | White solid; solubility in water: greater than 100 mg/mL; moderately soluble in methanol; insoluble in higher alcohols, acetone, ether; UV max absorption (water): 282 nm (e = 40, 1%, 1 cm) /Vancomycin hydrochloride/ |
| Purity | Purity information is available upon request (COA). |
| Synonym | VANCOMYCIN HYDROCHLORIDE; Vancomycin HCL; 1404-93-9; Vancomycin, monohydrochloride; Firvanq |
| IUPAC/Chemical Name | (1S,2R,18R,19R,22S,25R,28R,40S)-48-[(2S,3R,4S,5S,6R)-3-[(2S,4S,5S,6S)-4-amino-5-hydroxy-4,6-dimethyloxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-22-(2-amino-2-oxoethyl)-5,15-dichloro-2,18,32,35,37-pentahydroxy-19-[[(2R)-4-methyl-2-(methylamino)pentanoyl]amino]-20,23,26,42,44-pentaoxo-7,13-dioxa-21,24,27,41,43-pentazaoctacyclo[26.14.2.23,6.214,17.18,12.129,33.010,25.034,39]pentaconta-3,5,8(48),9,11,14,16,29(45),30,32,34(39),35,37,46,49-pentadecaene-40-carboxylic acid;hydrochloride |
| InChl Key | LCTORFDMHNKUSG-XTTLPDOESA-N |
| InChl Code | InChI=1S/C66H75Cl2N9O24.ClH/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92;/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95);1H/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-;/m0./s1 |
| References |
3D Conformer.
(Click, turn or enlarge)
Download our GMP API Product List.
MedicaPharma is an EU-based supplier of GMP-certified APIs that serves leading healthcare institutions and research organizations.
Click here to download our full API product list.
